9H-Pyrido[2,3-b]indole
α-carboline
CAS: 244-76-8
Molecular Formula: C11H8N2
9H-Pyrido[2,3-b]indole - Names and Identifiers
| Name | α-carboline |
| Synonyms | NSC 67064 α-carboline Α-CARBOLINE 1-Azacarbazole alpha-Carboline alpha-carboline 1,9-Diazafluorene 9H-1,9-Diazafluorene 9H-Pyrido[2,3-b]indole 9H-pyrido[2,3-b]indole 1H-Pyrido[2,3-b]indole 1,9-Diazafluorene 1-Azacarbazole 1H-Pyrido(2,3-b)indole (8CI)(9CI) |
| CAS | 244-76-8 |
| EINECS | 205-960-6 |
| InChI | InChI=1/C11H8N2/c1-2-6-10-8(4-1)9-5-3-7-12-11(9)13-10/h1-7H,(H,12,13) |
9H-Pyrido[2,3-b]indole - Physico-chemical Properties
| Molecular Formula | C11H8N2 |
| Molar Mass | 168.19 |
| Density | 1.301 |
| Melting Point | 210-212°C |
| Boling Point | 373℃ |
| Flash Point | 172℃ |
| Solubility | Acetone, DMSO, Methanol (Slightly, Hetaed) |
| Vapor Presure | 1.99E-05mmHg at 25°C |
| Appearance | Solid |
| Color | Pale Brown |
| Maximum wavelength(λmax) | 338nm(CH3CN)(lit.) |
| pKa | 14.53±0.30(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.784 |
9H-Pyrido[2,3-b]indole - Introduction
9H-Pyrido [2,3-b] Indole is an organic compound with the following properties:
1. Structure: It is composed of 9 carbon atoms and a nitrogen atom, showing a Spiro structure.
2. Physical properties: It is a solid, the color can be yellow or brown, with low solubility.
3. Chemical properties: it can react with other substances by heating or using chemical reactions. It is an alkaline substance that can react with acids to form the corresponding salts.
4. Uses: 9H-pyrido [2,3-b] Indole has important applications in the pharmaceutical field. It is a compound commonly used in cancer research and has anti-cancer activity. In addition, it is used as an intermediate in organic synthesis for the synthesis of other organic compounds.
5. Preparation method: 9H-pyrido [2,3-b] Indole can be prepared by a variety of synthetic methods, the most commonly used of which is a multi-step synthesis under alkaline conditions. This synthesis process requires special equipment and techniques in the organic chemistry laboratory.
6. Safety information: The following safety precautions should be paid attention to when handling 9H-pyrido [2,3-b] Indole: wear gloves, goggles and laboratory clothing when using; Avoid inhalation of dust or contact with skin; storage should be sealed, away from fire and oxidant. If ingested or inhaled by mistake, seek medical attention immediately. When using or handling this compound in the laboratory, chemical safety procedures should be followed and waste should be disposed of properly.
1. Structure: It is composed of 9 carbon atoms and a nitrogen atom, showing a Spiro structure.
2. Physical properties: It is a solid, the color can be yellow or brown, with low solubility.
3. Chemical properties: it can react with other substances by heating or using chemical reactions. It is an alkaline substance that can react with acids to form the corresponding salts.
4. Uses: 9H-pyrido [2,3-b] Indole has important applications in the pharmaceutical field. It is a compound commonly used in cancer research and has anti-cancer activity. In addition, it is used as an intermediate in organic synthesis for the synthesis of other organic compounds.
5. Preparation method: 9H-pyrido [2,3-b] Indole can be prepared by a variety of synthetic methods, the most commonly used of which is a multi-step synthesis under alkaline conditions. This synthesis process requires special equipment and techniques in the organic chemistry laboratory.
6. Safety information: The following safety precautions should be paid attention to when handling 9H-pyrido [2,3-b] Indole: wear gloves, goggles and laboratory clothing when using; Avoid inhalation of dust or contact with skin; storage should be sealed, away from fire and oxidant. If ingested or inhaled by mistake, seek medical attention immediately. When using or handling this compound in the laboratory, chemical safety procedures should be followed and waste should be disposed of properly.
Last Update：2024-04-09 20:52:54
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